구분 : SCIE
학술지명 : Nanoscale Research Letters
논문명 : Efficient CD44-targeted magnetic resonance imaging (MRI) of breast cancer cells using hyaluronic acid (HA)-modified MnFe2O4 nanocrystals
저자 : Taeksu Lee, Eun-Kyung Lim, Jaemin Lee, Byunghoon Kang, Jihye Choi, Hyo Seon Park, Jin-Suck Suh, Yong-Min Huh, Seungjoo Haam
논문번호 : 8(149)
게재년월 : 2013.04

Targeted molecular imaging with hyaluronic acid (HA) has been highlighted in the diagnosis and treatment of CD44-overexpressing cancer. CD44, a receptor for HA, is closely related to the growth of cancer including proliferation, metastasis, invasion, and angiogenesis. For the efficient detection of CD44, we fabricated a few kinds of HA-modified MnFe2O4 nanocrystals (MNCs) to serve as specific magnetic resonance (MR) contrast agents (HA-MRCAs) and compared physicochemical properties, biocompatibility, and the CD44 targeting efficiency. Hydrophobic MNCs were efficiently phase-transferred using aminated polysorbate 80 (P80) synthesized by introducing spermine molecules on the hydroxyl groups of P80. Subsequently, a few kinds of HA-MRCAs were fabricated, conjugating different ratios of HA on the equal amount of phase-transferred MNCs. The optimized conjugation ratio of HA against magnetic content was identified to exhibit not only effective CD44 finding ability but also high cell viability through in vitro experiments. The results of this study demonstrate that the suggested HA-MRCA shows strong potential to be used for accurate tumor diagnosis. 

구분 : SCI
학술지명 : Journal of Materials Chemistry A
논문명 : One-step electrochemical fabrication of vertically self-organized silver nanograss
저자 : Doyeon Bang, Young Wook Chang, Joseph Park, Taeksu Lee, Jiyun Park, Jong-Souk Yeo, Eun-Kyung Kim, Kyung-Hwa Yoo, Yong-Min Huh, Seungjoo Haam
논문번호 : 1(15):4851-4857
게재년월 : 2013.04

Fabrication of one dimensional metal nanomaterials offers many beneficial aspects due to their unique size- and shape-dependent characteristics. However, facile fabrication of a robust one dimensional nanostructure has still remained a great challenge. Here, we developed a new synthetic route of onestep electrochemical deposition of silver nanograss without the assistance of a template. By applying an overpotential of  2.0 V (vs. Ag/AgCl) under aqueous alkaline conditions, silver nanograss with a slight tilt in a randomly oriented direction was spontaneously formed on the working electrode surface. Two applications that utilize advantageous features of this silver nanograss were demonstrated: (i) an efficient surface-enhanced Raman scattering substrate for a chemical sensor and (ii) an enzyme-less hydrogen peroxide sensor. Compared to silver nanowire arrays fabricated using anodized aluminum oxide (AAO) templates, the silver nanograss exhibited comparable hydrogen sensing due to its catalytic hydrogen peroxide reduction activity and produced a much stronger surface-enhanced Raman spectroscopy (SERS) signal due to its innate structure. 

구분 : Journal
학술지명 : 한국화상학회지
논문명 : 자성 나노 입자의 조절을 통한 MR 이미징에서의 T2 이완도 증강
저자 : 노영준, 박요셉, 강병훈, 이재민, 허용민, 함승주
논문번호 : 19(1):1-12
게재년월 : 2013.03

 We describe the preparation of superparamagnetic nanoclusters (SNCs) by fine-tuning of the seed Fe3O4 nanoparticle sizes to enhance and their T2 relaxivity can be increased by > 4-fold. Therefore, with 11 nm seed core and PVA coating, SNC-11 exhibit a higher T2 relaxivity than other cluster condition. So fabricating the cluster, seed size is the most important influence the T2 relaxivity. As well as, in vitro cellular imaging results demonstrated the strong potential of SNCs for clinical applications by targeting affinity. According to the experiments, with 11 nm seed core and PVA coating, SNC-11 exhibited the highest T2 relaxivity of 454 mM-1s-1 due to the strong seed size effect on their magnetic sensitivity, indicating superior magnetic resonance (MR) contrast efficiency. Further in vitro cellular imaging results demonstrated the strong potential of SNCs for clinical applications. 

구분 : SCI
학술지명 : Journal of Materials Chemistry B
논문명 : Magnetic nanocomplexes and the physiologicalchallenges associated with their use for cancer imagingand therapy
저자 : Eunjung Kim, Kwangyeol Lee, Yong-Min Huh, Seungjoo Haam
논문번호 : 1(6):729-739
게재년월 : 2013.02

5.968 (JCR 2011) 

구분 : SCIE
학술지명 : Nanoscale Research Letters
논문명 : Double-ligand modulation for engineering magnetic nanoclusters
저자 : Bongjune Kim, Jaemoon Yang, Eun-Kyung Lim, Joseph Park, Jin-Suck Suh, Hyo Seon Park, Yong-Min Huh, Seungjoo Haam
논문번호 : 8(104)
게재년월 : 2013.02 Magnetic nanoclusters (MNCs) are agglomerated individual magnetic nanoparticles (MNPs) that show great promise in increasing magnetic resonance imaging (MRI) sensitivity. Here, we report an effective strategy to engineer MNCs based on double-ligand modulation to enhance MRI sensitivity. The oleic acid-coated individual MNPs self-assembled and then were enveloped by polysorbate 80, using a nanoemulsion method to prepare MNCs. By modulating the amounts of the two ligands, and thus the size and magnetic content of the resultant MNCs, we were able to enormously improve MRI sensitivity. 

구분 : SCI
학술지명 : European Journal of Inorganic Chemistry
논문명 : Effect of Ligand Structure on MnO Nanoparticles for Enhanced T1 Magnetic Resonance Imaging of Inflammatory Macrophages
저자 : Joseph Park, Doyeon Bang, Eunjung Kim, Jaemoon Yang, Eunkyung Lim, Jihye Choi, Byunghoon Kang, Jin-Suck Suh, Hyo Seon Park, Yong-Min Huh, Seungjoo Haam
논문번호 : Vol. 2012(36):5960-5965
게재년월 : 2012.12

3.049 

구분 : SCI
학술지명 : Nanotechnology
논문명 : Role of surface charge in cytotoxicity of charged manganese ferrite nanoparticles towards macrophages
저자 : Seung-Hyun Yang, Dan Heo, Jinsung Park, Sungsoo Na, Jin-Suck Suh, Seungjoo Ham, Sahng Wook Park, Yong-Min Huh, Jaemoon Yang
논문번호 : 23(50):505702
게재년월 : 2012.12

3.979

구분 : SCIE
학술지명 : Biochip Journal
논문명 : Water-stable single-walled carbon nanotubes coated by pyrenyl polyethylene glycol for fluorescence imaging and photothermal therapy
저자 : Keuwhan Jang, Kilho Eom, Gyudo Lee, Jae-Hee Han, Seungjoo Haam, Jaemoon Yang, Eunseon Kin, Woo-Jae Kim, Taeyun Kwon
논문번호 : 6(4):393-403
게재년월 : 2012.12 0.86

구분 : SCI
학술지명 : Journal of Gastroenterology and Hepatology
논문명 : N-3 polyunsaturated fatty acid attenuates cholesterol gallstones by suppressing mucin production with a high cholesterol diet in mice
저자 : Ja Kyung Kim, Soo Min Cho, So Hee Kang, Eunjung Kim, Hee Yi, Eun Sun Yun, Dong Goo Lee, Hee Jung Cho, Yong Han Paik, Yang Kyu Choi, Seung Joo Haam, Ho Chul Shin, Dong Ki Lee
논문번호 : Vol. 27(11):1745-1751
게재년월 : 2012.11

  

구분 : SCI
학술지명 : Nanotechnology
논문명 : Highly selective CD44-specific gold nanorods for photothermal ablation of tumorigenic subpopulations generated in MCF7 mammospheres
저자 : Eugene Lee, Yoochan Hong, Jihye Choi, Seungjoo Haam, Jin-Suck Suh, Yong-Min Huh, Jaemoon Yang
논문번호 : Vol. 23(46):465101
게재년월 : 2012.11

  

구분 : SCIE
학술지명 : Journal of Nanomaterials
논문명 : Gold Nanorod-Mediated Photothermal Modulation for Localized Ablation of Cancer Cells
저자 : Yoochan Hong, Eugene Lee, Jihye Choi, Seung Jae Oh, Seungjoo Haam, Yong-Min Huh, Dae Sung Yoon, Jin-Suck Suh, Jaemoon Yang
논문번호 : Vol. 2012
게재년월 : 2012.11 1.376

구분 : SCI
학술지명 : ACS Nano
논문명 : Consecutive Targetable Smart Nanoprobe for Molecular Recognition of Cytoplasmic microRNA in Metastatic Breast Cancer
저자 : Eunjung Kim, Jaemoon Yang, Joseph Park, Soonhag Kim, Nam Hee Kim, Jong In Yook, Jin-Suck Suh, Seungjoo Haam, Yong-Min Huh
논문번호 : Vol. 6(10):8525-8535
게재년월 : 2012.10

 

구분 : SCI
학술지명 : Biomaterials
논문명 : A reverse complementary multimodal imaging system to visualize microRNA9-involved neurogenesis using peptide targeting transferrin receptor-conjugated magnetic fluorescence nanoparticles
저자 : Mi-hee Jo, Bahy A. Ali, Abdulaziz A. Al-Khedhairy, Chang Hyun Lee, Bongjune Kim, Seungjoo Haam, Yong-Min Huh, Hae Young Ko, Soonhag Kim
논문번호 : Vol. 33(27):6456-6467
게재년월 : 2012.09

  

구분 : SCI
학술지명 : Thin Solid Films
논문명 : Fabrication of a near-infrared sensor using a polyaniline conducting polymer thin film
저자 : Doyeon Bang, Young Wook Chang, Joseph Park, Jaemin Lee, Kyung-Hwa Yoo, Yong-Min Huh, Seungjoo Haam
논문번호 : Vol. 520(22):6818-6821
게재년월 : 2012.09

  

구분 : SCI
학술지명 : Nanotechnology
논문명 : The work function of doped polyaniline nanoparticles observed by Kelvin probe force microscopy
저자 : Jinsung Park, Doyeon Bang, Kuewhan Jang, Seungjoo Haam, Jaemoon Yang, Sungsoo Na
논문번호 : 23:365705-365712
게재년월 : 2012.09

 

구분 : SCI
학술지명 : Journal of Materials Chemistry
논문명 : Self-fabricated dextran-coated gold nanoparticles using pyrenyl dextran as a reducible stabilizer and their application as CT imaging agents for atherosclerosis
저자 : Eun-Kyung Lim, Eunji Jang, Jeonghun Kim, Taeksu Lee, Eunkyoung Kim, Hyo Seon Park, Jin-Suck Suh, Yong-Min Huh, Seungjoo Haam
논문번호 : Vol. 22(34):17518?17524
게재년월 : 2012.09

  

구분 : SCI
학술지명 : Stem Cells and Development
논문명 : β-PIX is critical for transplanted mesenchymal stromal cell migration
저자 : Seong-Ho Koh, Yong-Min Huh, Min Young Noh, Hun Young Kim, Kyung Suk Kim, Eun-Sook Lee, Hyun-Ju Ko, Goang Won Cho, A Rum Yoo, Ho-taek Song, Sejin Hwang, Kwangyeol Lee, Seungjoo Haam, Joseph A Frank, Jin-Suck Suh, Seung Hyun Kim
논문번호 : Vol. 21(11):1989-1999
게재년월 : 2012.07 <P>&nbsp;&nbsp;</P>

구분 : SCI
학술지명 : Angewandte Chemie-International Edition
논문명 : Real-Time Quantitative Monitoring of Specific Peptide Cleavage by a Proteinase for Cancer Diagnosis
저자 : Gyudo Lee, Kilho Eom, Joseph Park, Jaemoon Yang, Seungjoo Haam, Yong-Min Huh, Joo Kyung Ryu, Nam Hee Kim, Jong In Yook, Sang Woo Lee, Dae Sung Yoon, Taeyun Kwon
논문번호 : Vol. 51(24):5837 ?5841
게재년월 : 2012.06

  

구분 : SCI
학술지명 : Small
논문명 : Targetable Gold Nanorods for Epithelial Cancer Therapy Guided by Near-IR Absorption Imaging
저자 : Jihye Choi, Jaemoon Yang, Doyeon Bang, Joseph Park, Jin-Suck Suh,Yong-Min Huh,* and Seungjoo Haam
논문번호 : 8, No. 5, 746?753
게재년월 : 2012.03

구분 : SCI
학술지명 : Journal or Materials Chemistry
논문명 : Effectively enhanced sensitivity of a polyaniline?carbon nanotube composite thin film bolometric near-infrared sensor
저자 : Doyeon Bang, Jaemin Lee, Joseph Park, Jihye Choi, Young Wook Chang, Kyung-Hwa Yoo, Yong-Min Huh and Seungjoo Haam
논문번호 : 22, 3215?3219
게재년월 : 2012.03